Scientists in Barcelona discovered why a boron-rich molecule called o-FESAN can stick to DNA, even though its charge should push it away. The molecule's many weak bonds work like Velcro, overcoming the repulsion.
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A counterintuitive molecular behavior opens new possibilities for cancer radiotherapy
Counterintuitive Molecule binds to DNA
Velcro Effect Multiple weak bonds overcome charge repulsion
Cancer Treatment Discovery enables targeted radiotherapy
Barcelona, Spain Research institution
20% boron-10 content
2 boron isotopes targeted
Far Smaller radiation doses reduced