Scientists found a way to stop lung cancer from resisting radiation therapy. The MD Anderson team discovered that the enzyme DHODH shields cancer cells, but adding leflunomide—a DHODH-blocking arthritis drug already approved by
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Novel strategy enables protection against radiation therapy resistance in lung cancer
DHODH Enzyme blocking radiation resistance
Leflunomide (Arthritis Drug) Drug that reverses resistance
Radiation + Immunotherapy + Leflunomide Triple therapy approach
FDA-Approved drug status
3 therapy components