A comparative study presented at ESGE Days 2026 found that endoscopic sleeve gastroplasty (ESG) produces significantly greater short-term weight loss than oral semaglutide in adults with obesity.
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Endoscopic procedure associated with greater short-term weight loss than oral semaglutide, study finds

ESG Outperforms Oral Semaglutide Procedure comparison
Adults With Obesity Target population
Short-Term Weight Loss Timeframe