A Chinese research team led by Peking University scientists has developed HEP-50768, a first-in-class drug candidate for chronic itch associated with cholestatic liver disease.
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Scientists develop first-in-class drug candidate for chronic itch

MRGPRX4 Itch Receptor Drug target
HEP-50768 Compound name
Reduced Scratching Behavior Animal efficacy
Filed IND status
Planned Phase I trials
100,000+ molecules screened