Sweden's first double-blind, randomized study on psilocybin for depression shows a single 25mg dose produced rapid symptom relief within days.
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Single dose of psilocybin provides rapid relief from depression in double-blind study

35 participants Study size
53 % Remission at 6 weeks
3+ months Effect duration
25 mg Dose
9.7 points MADRS improvement
25mg single dose
9.7 Points MADRS reduction