Stem-cell memory T (TSCM) cells demonstrate potential for next-generation CAR T-cell therapies, achieving complete remissions without chemotherapy at doses as low as 250,000 cells/kg in humans for the first time.
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Why this CAR T advance matters: Complete remissions without chemotherapy at doses as low as 250,000 cells/kg
Stem-Cell Memory T (TSCM) Cells Cell type used
250,000 Cells/Kg cells/kg Therapeutic dose
Complete Remissions Without Chemotherapy Clinical outcome
Self-Renewing And Long-Term Persistent Key property
0% chemotherapy required